翻訳と辞書 Words near each other ・ Sterling Heights High School ・ Stericta kiiensis ・ Stericta rufescens ・ Stericta rurealis ・ Stericta subviridalis ・ Stericycle ・ Sterigma ・ Sterigmatocystin ・ Sterigmatocystin 8-O-methyltransferase ・ Sterijino ・ Sterijino pozorje ・ Steriker Hare ・ Steril ・ Steril (band) ・ Sterilant gas monitoring ・ Sterile alpha motif ・ Sterile Cockpit Rule ・ Sterile deposit ・ Sterile fungi ・ Sterile insect technique ・ Sterile Island ・ Sterile male plant ・ Sterile neutrino ・ Sterile Records ・ Sterile talc powder ・ Sterilgarda ・ Sterilite ・ Sterility ・ Sterility (physiology) ・ Sterility assurance level Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Sterile alpha motif ： ウィキペディア英語版 Sterile alpha motif In molecular biology, the protein domain Sterile alpha motif (or SAM) is a putative protein interaction module present in a wide variety of proteins involved in many biological processes. The SAM domain that spreads over around 70 residues is found in diverse eukaryotic organisms. SAM domains have been shown to homo- and hetero-oligomerise, forming multiple self-association architectures and also binding to various non-SAM domain-containing proteins, nevertheless with a low affinity constant. SAM domains also appear to possess the ability to bind RNA. Smaug a protein that helps to establish a morphogen gradient in Drosophila embryos by repressing the translation of nanos (nos) mRNA binds to the 3' untranslated region (UTR) of nos mRNA via two similar hairpin structures. The 3D crystal structure of the Smaug RNA-binding region shows a cluster of positively charged residues on the Smaug-SAM domain, which could be the RNA-binding surface. This electropositive potential is unique among all previously determined SAM-domain structures and is conserved among Smaug-SAM homologs. These results suggest that the SAM domain might have a primary role in RNA binding. Structural analyses show that the SAM domain is arranged in a small five-helix bundle with two large interfaces.〔 In the case of the SAM domain of EPHB2, each of these interfaces is able to form dimers. The presence of these two distinct intermonomers binding surface suggest that SAM could form extended polymeric structures.〔 ==Fungal SAM== In molecular biology, the protein domain Ste50p mainly in fungi and some other types of eukaryotes. It plays a role in the mitogen-activated protein kinase cascades, a type of cell signalling that helps the cell respond to external stimuli, more specifically mating, cell growth, and osmo-tolerance in fungi. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Sterile alpha motif」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.